Jonathan I Epstein Selected Research

Prostatic Intraepithelial Neoplasia

1/2021	The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer.
10/2013	Two sequential diagnoses of atypical foci suspicious for carcinoma on prostate biopsy: a follow-up study of 179 cases.
4/2013	Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia.
3/2013	Small cell-like change in prostatic intraepithelial neoplasia, intraductal carcinoma, and invasive prostatic carcinoma: a study of 7 cases.
12/2012	Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling.
8/2011	Initial high-grade prostatic intraepithelial neoplasia with carcinoma on subsequent prostate needle biopsy: findings at radical prostatectomy.
7/2008	High-grade prostatic intraepithelial neoplasialike ductal adenocarcinoma of the prostate: a clinicopathologic study of 28 cases.
10/2004	Characterization of minute adenocarcinomas of prostate at radical prostatectomy.
9/2003	Hypermethylation of the human glutathione S-transferase-pi gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: a detailed study using laser-capture microdissection.
7/2003	Immunohistochemical staining of prostate cancer with monoclonal antibodies to the precursor of prostate-specific antigen.

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Jonathan I Epstein Research Topics

Disease

203	Neoplasms (Cancer) 01/2022 - 03/2002
141	Prostatic Neoplasms (Prostate Cancer) 10/2021 - 03/2002
66	Carcinoma (Carcinomatosis) 12/2022 - 02/2002
66	Adenocarcinoma 01/2021 - 02/2002
29	Neoplasm Metastasis (Metastasis) 01/2022 - 12/2003
21	Margins of Excision 02/2017 - 01/2002
16	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 02/2003
11	Prostatic Intraepithelial Neoplasia 01/2021 - 09/2002
10	Necrosis 01/2021 - 01/2004
8	Disease Progression 01/2018 - 12/2003
8	Hyperplasia 01/2016 - 02/2002
7	Lymphatic Metastasis 12/2013 - 11/2004
6	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2021 - 12/2006
6	Cysts 10/2018 - 05/2006
6	Atrophy 04/2017 - 09/2003
5	Small Cell Carcinoma 01/2018 - 01/2008
5	Hemorrhage 11/2016 - 07/2004
5	Residual Neoplasm 06/2008 - 04/2005
4	Leiomyomatosis 01/2021 - 11/2014
4	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 04/2013
4	Obesity 04/2016 - 03/2005
4	Inflammation (Inflammations) 01/2016 - 07/2004
3	Clear Cell Adenocarcinoma 01/2021 - 04/2010
3	Chronic Kidney Failure (Chronic Renal Failure) 10/2018 - 02/2003
3	Medullary Carcinoma 01/2018 - 08/2009
3	Testicular Neoplasms (Testicular Cancer) 01/2018 - 09/2009
3	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 11/2015 - 11/2008
3	Acinar Cell Carcinoma 10/2015 - 06/2011
3	Seminoma 04/2014 - 11/2008
2	Prostatitis 01/2020 - 02/2010
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2019 - 07/2006
2	Granular Cell Tumor 11/2018 - 02/2013
2	Choriocarcinoma 01/2018 - 11/2015
2	Metaplasia 04/2017 - 07/2006

Drug/Important Bio-Agent (IBA)

89	Prostate-Specific Antigen (Semenogelase)IBA 01/2021 - 01/2002
26	Keratins (Keratin)IBA 12/2019 - 09/2002
20	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2003
20	Biomarkers (Surrogate Marker)IBA 01/2021 - 07/2002
11	DNA (Deoxyribonucleic Acid)IBA 05/2019 - 12/2003
10	Biological ProductsIBA 01/2021 - 06/2002
10	ParaffinIBA 01/2018 - 03/2003
9	alpha-methylacyl-CoA racemaseIBA 02/2016 - 06/2003
8	Hormones (Hormone)IBA 01/2020 - 03/2005
8	AndrogensIBA 12/2015 - 11/2006
7	Formaldehyde (Formol)FDA Link 01/2018 - 09/2003
7	Racemases and Epimerases (Epimerases and Racemases)IBA 08/2013 - 07/2006
6	ChromatinIBA 01/2021 - 12/2003
6	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 03/2003
6	MucinsIBA 11/2013 - 07/2006
5	Phenobarbital (Luminal)FDA Link 01/2021 - 05/2007
5	Fumarate Hydratase (Fumarase)IBA 01/2021 - 11/2016
5	Dihydrotachysterol (AT 10)IBA 10/2015 - 07/2006
5	Hematoxylin (Haematoxylon)IBA 09/2010 - 09/2002
5	Eosine Yellowish-(YS) (Eosin)IBA 09/2010 - 09/2002
5	AntibodiesIBA 08/2010 - 06/2003
5	Coloring Agents (Dyes)IBA 06/2008 - 09/2002
4	ChromograninsIBA 01/2021 - 01/2004
4	SynaptophysinIBA 01/2021 - 01/2004
4	prosteinIBA 01/2020 - 09/2007
4	Messenger RNA (mRNA)IBA 03/2015 - 10/2007
3	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2021 - 10/2013
3	CateninsIBA 12/2019 - 07/2011
3	DesminIBA 12/2019 - 07/2008
3	Cadherins (E-Cadherin)IBA 12/2019 - 05/2005
3	Indicators and Reagents (Reagents)IBA 01/2018 - 09/2011
3	Colloids (Colloid)IBA 01/2018 - 07/2008
3	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 03/2015 - 04/2013
3	Estrogen ReceptorsIBA 01/2015 - 04/2010
3	Keratin-7 (Cytokeratin 7)IBA 11/2014 - 04/2009
3	Fluconazole (Zonal)FDA LinkGeneric 01/2014 - 09/2002
3	Coenzyme A (CoA)IBA 03/2012 - 06/2007
3	HemosiderinIBA 09/2011 - 07/2004
3	Glutathione S-Transferase piIBA 08/2004 - 09/2003
2	GP 4 (GP4)IBA 01/2021 - 12/2016
2	Anaplastic Lymphoma KinaseIBA 01/2021 - 01/2021
2	RNA (Ribonucleic Acid)IBA 01/2020 - 12/2018
2	Chromogranin AIBA 01/2020 - 12/2008
2	Keratin-20 (Cytokeratin 20)IBA 12/2019 - 09/2003
2	Immune Checkpoint InhibitorsIBA 12/2019 - 05/2019
2	Keratin-8 (Keratin 8)IBA 12/2019 - 06/2013
2	S100 Proteins (S 100 Protein)IBA 11/2018 - 06/2006
2	Calcium OxalateIBA 10/2018 - 02/2003
2	Cyclin D1IBA 12/2017 - 12/2015
2	Uroplakin IIIBA 11/2017 - 01/2015
2	Technetium Tc 99m Sestamibi (Cardiolite)FDA LinkGeneric 10/2017 - 04/2017
2	Carrier Proteins (Binding Protein)IBA 01/2017 - 01/2015

Therapy/Procedure

160	Prostatectomy (Retropubic Prostatectomy) 01/2022 - 01/2002
43	Therapeutics 01/2021 - 02/2002
16	Drug Therapy (Chemotherapy) 01/2021 - 07/2004
14	Cystectomy 12/2022 - 02/2002
9	Radiotherapy 01/2020 - 02/2003
8	Lymph Node Excision (Lymph Node Dissection) 11/2018 - 05/2003
7	Nephrectomy 01/2019 - 10/2004
4	Orchiectomy (Orchidectomy) 01/2018 - 09/2009
4	Transurethral Resection of Prostate (TURP) 10/2015 - 08/2007
3	Castration 01/2020 - 11/2011
3	Adjuvant Chemotherapy 11/2016 - 07/2011
2	Immunotherapy 01/2021 - 11/2017
2	Contraindications 01/2020 - 12/2010
2	Nephroureterectomy 01/2017 - 04/2006